The MWCSD
Sleep Blog
Expert perspectives on sleep medicine, research breakthroughs, and practical advice — written by our board-certified physicians.
Before Starting Xywav or Lumryz, Ask Yourself: How Did Your Body Respond to These Other Medications?
Your prior response to baclofen, gabapentin, or benzodiazepines may reveal meaningful signals about whether Xywav or Lumryz will work for you — but the hierarchy of which drugs matter most as predictors is not what most clinicians assume. Dr. Vishal Saini explains the pharmacological reasoning.
"Benadryl Knocks Me Out Cold" — Does That Mean Pitolisant Will Work Well for You? The Science Says: Not So Fast.
If antihistamines knock you out, does that mean pitolisant will supercharge your wakefulness? The pharmacology says no — and understanding why reveals something important about how narcolepsy and IH affect the histamine system. Dr. Vishal Saini explains the science.
What Your Deep Sleep Percentage Actually Tells Us — And Why It May Predict Whether Oxybate Works for You
Your N3 slow-wave sleep percentage on a sleep study may be one of the most important biomarkers for predicting oxybate response — but the story is fundamentally different for Narcolepsy vs. Idiopathic Hypersomnia. Dr. Vishal Saini explains the emerging science and what it means for your treatment.
MWCSD Now Enrolling: Brilliance Phase III Clinical Trial for Narcolepsy
Mid-West Center for Sleep Disorders is proud to announce the launch of the Brilliance Phase III clinical trial for narcolepsy, sponsored by Alkermes. We are now actively enrolling qualified patients across our Michigan locations.
Introducing The Hidden Sleep Disorders Show
Dr. Vishal Saini launches a new podcast dedicated to uncovering the medical conditions hiding behind unexplained fatigue and poor sleep.
Newsletter
Never miss a new article
Get a quick email whenever we publish new content — no spam, just sleep science.
Ready to Sleep Better?
Reading is a start — but lasting change comes from expert care. Book a consultation with our board-certified sleep physicians.
Book an Appointment